Package: SKAT
Type: Package
Title: SNP-Set (Sequence) Kernel Association Test
Version: 2.2.4
Date: 2022-03-29
Authors@R: c(person("Seunggeun (Shawn)", "Lee", role = c("aut", "cre", "cph"), email = "lee7801@snu.ac.kr"),
             person("Zhangchen", "Zhao", role = c("aut")),
             person("Larisa", "Miropolsky", role = c("aut")),
             person("Michael", "Wu", role = c("aut")))
Maintainer: Seunggeun (Shawn) Lee <lee7801@snu.ac.kr>
Description: Functions for kernel-regression-based association tests including Burden test, SKAT and SKAT-O. These methods aggregate individual SNP score statistics in a SNP set and efficiently compute SNP-set level p-values. Methods  available in this package include SKAT described in Micheal Wu, Seunggeun Lee et al. (2011) <doi:10.1016/j.ajhg.2011.05.029>, SKAT-O in Seunggeun Lee et al. (2012) <doi:10.1093/biostatistics/kxs014>, combined test of rare and common variants in Iuliana Ionita-Laza and Seunggeun Lee et al. (2013) <doi:10.1016/j.ajhg.2013.04.015>, efficient resampling for binary traits in Seunggeun Lee et al. (2016) <doi:10.1093/biostatistics/kxv033>, and robust test for binary traits in Zhangchen Zhao et al. (2020) <doi:10.1016/j.ajhg.2019.11.012>.
License: GPL (>= 2)
Depends: R (>= 2.13.0), Matrix, SPAtest, RSpectra
LazyData: yes
NeedsCompilation: yes
Packaged: 2022-03-29 08:45:25 UTC; lee7801
Author: Seunggeun (Shawn) Lee [aut, cre, cph],
  Zhangchen Zhao [aut],
  Larisa Miropolsky [aut],
  Michael Wu [aut]
Repository: CRAN
Date/Publication: 2022-03-29 12:50:07 UTC
Built: R 4.1.3; x86_64-w64-mingw32; 2022-03-29 23:07:13 UTC; windows
Archs: x64
