R: Random effects (DerSimonian-Laird) meta-analysis

meta.DSL {rmeta} | R Documentation

## Random effects (DerSimonian-Laird) meta-analysis

### Description

Computes the individual odds ratios or relative risks, the summary, the random effects variance, and Woolf's test for heterogeneity. The `print` method gives the summary and test for heterogeneity; the `summary` method also gives all the individual odds ratios and confidence intervals. Studies with zero or infinite odds ratio are omitted, as their variance cannot be calculated sensibly.

The `plot` method draws a standard meta-analysis plot. The confidence interval for each study is given by a horizontal line, and the point estimate is given by a square whose height is inversely proportional to the standard error of the estimate. The summary odds ratio, if requested, is drawn as a diamond with horizontal limits at the confidence limits and width inversely proportional to its standard error.

### Usage

    meta.DSL(ntrt, nctrl, ptrt, pctrl, conf.level=0.95,
             names=NULL, data=NULL, subset=NULL, na.action=na.fail,statistic="OR")
    ## S3 method for class 'meta.DSL'
    summary(object, conf.level=NULL, ...)
    ## S3 method for class 'meta.DSL'
    plot(x, summary=TRUE, summlabel="Summary",
                 conf.level=NULL, colors=meta.colors(), xlab=NULL,...)

### Arguments

`ntrt` | Number of subjects in treated/exposed group
`nctrl` | Number of subjects in control group
`ptrt` | Number of events in treated/exposed group
`pctrl` | Number of events in control group
`conf.level` | Coverage for confidence intervals
`names` | names or labels for studies
`data` | data frame to interpret variables
`subset` | subset of studies to include
`na.action` | a function which indicates what should happen when the data contain `NA`s. Defaults to `na.fail`.
`statistic` | "OR" for odds ratio, "RR" for relative risk
`x,object` | a `meta.DSL` object
`summary` | Plot the summary odds ratio?
`summlabel` | Label for the summary odds ratio
`colors` | see `meta.colors`
`xlab` | x-axis label, default is based on `statistic`
`...` | further arguments to be passed from or to methods.

### Value

An object of class `meta.DSL` with `print`, `plot`, `funnelplot` and `summary` methods.

### Author(s)

Thomas Lumley

### See Also

`plot`,`par`,`meta.MH`,`funnelplot`

### Examples

    data(catheter)
    b <- meta.DSL(n.trt, n.ctrl, col.trt, col.ctrl, data=catheter,
                  names=Name, subset=c(13,6,5,3,7,12,4,11,1,8,10,2))
    b
    summary(b)
    plot(b)
    e <- meta.DSL(n.trt, n.ctrl, inf.trt, inf.ctrl, data=catheter,
                  names=Name, subset=c(13,6,3,12,4,11,1,14,8,10,2))
    e
    summary(e)
    ##tasteless
    plot(e, colors=meta.colors(summary="green",lines="purple",box="orange"))

[Package rmeta version 2.16 Index]