R: Coverage histogram of a scWGS data

SRR611492 {preseqR} | R Documentation

## Coverage histogram of a scWGS data

### Description

The coverage histogram is based on a single-cell whole-genome sequencing data (scWGS) through MALBAK protocol. The accession number of the raw data is SRR1301329. Only forward reads are used to generate the coverage histogram.

### Details

A two-column matrix. The first column is the frequency j = 1,2,…; and the second column is N_j, the number of nucleotides in the genome covered exactly j times.

### References

Zong, C., Lu, S., Chapman, A. R., & Xie, X. S. (2012). Genome-wide detection of single-nucleotide and copy-number variations of a single human cell. Science, 338(6114), 1622-1626.

### Examples

    ##load library
    library(preseqR)

    ##load data
    data(SRR611492)

[Package preseqR version 4.0.0 Index]