R: Coverage histogram of a scWGS data

SRR611492_5M {preseqR} | R Documentation

## Coverage histogram of a scWGS data

### Description

The coverage histogram is based on a single-cell whole-genome sequencing (scWGS) data through MALBAK protocol. The accession number of the raw data is SRR1301329. Five million reads are randomly sampled from the raw data to generate this coverage histogram.

### Details

A two-column matrix. The first column is the frequency j = 1,2,…; and the second column is N_j, the number of nucleotides in the genome covered exactly j times.

### References

Zong, C., Lu, S., Chapman, A. R., & Xie, X. S. (2012). Genome-wide detection of single-nucleotide and copy-number variations of a single human cell. Science, 338(6114), 1622-1626.

### Examples

    ##load library
    library(preseqR)

    ##load data
    data(SRR1301329_5M)

[Package preseqR version 4.0.0 Index]