R: Compute the Z-scales of a protein sequence

zScales {Peptides} | R Documentation

## Compute the Z-scales of a protein sequence

### Description

Z-scales are based on physicochemical properties of the AAs including NMR data and thin-layer chromatography (TLC) data.

### Usage

    zScales(seq)

### Arguments

`seq` | An amino-acids sequence

### Value

The computed average of Z-scales of all the amino acids in the corresponding peptide sequence. Each Z scale represent an amino-acid property as follows:

- Z1: Lipophilicity

- Z2: Steric properties (Steric bulk/Polarizability)

- Z3: Electronic properties (Polarity / Charge)

- Z4 and Z5: They relate electronegativity, heat of formation, electrophilicity and hardness.

### References

Sandberg M, Eriksson L, Jonsson J, Sjostrom M, Wold S: New chemical descriptors relevant for the design of biologically active peptides. A multivariate characterization of 87 amino acids. J Med Chem 1998, 41:2481-2491.

### Examples

    zScales(seq = "QWGRRCCGWGPGRRYCVRWC")
    # [[1]]
    #  Z1      Z2      Z3      Z4      Z5
    # 0.6200  0.0865  0.0665  0.7280 -0.8740

[Package Peptides version 2.4.4 Index]