R: Normalisation of metabolomic data

normalise {mQTL}

R Documentation

Normalisation of metabolomic data

Description

Removing dilutions between biofluid samples (normalisation of spectra)

Usage

normalise(X, method)

Arguments

`X`	metabolomic data
`method`	total area (method<-"total") or quotient probabilistic method (method<-"prob")

Value

normalised spectrum

Author(s)

Lyamine Hedjazi

References

Dieterle,F., et al (2006) Probabilistic Quotient Normalization as Robust Method to Account for Dilution of Complex Biological Mixtures. Application in 1H NMR Metabonomics, Anal. Chem., 78(13), 42814290.

Examples


## Data
Sp=matrix(rnorm(10*13454,mean=0,sd=1), nrow=10,ncol=13454)

## Quotient probabilistic normalisation
NormDat<-normalise(abs(Sp),'prob')

[Package mQTL version 1.0 Index]