R: Normalisation of metabolomic data

normalise {mQTL} | R Documentation

## Normalisation of metabolomic data

### Description

Removing dilutions between biofluid samples (normalisation of spectra)

### Usage

    normalise(X, method)

### Arguments

`X` | metabolomic data
`method` | total area (method<-"total") or quotient probabilistic method (method<-"prob")

### Value

normalised spectrum

### Author(s)

Lyamine Hedjazi

### References

Dieterle,F., et al (2006) Probabilistic Quotient Normalization as Robust Method to Account for Dilution of Complex Biological Mixtures. Application in 1H NMR Metabonomics, Anal. Chem., 78(13), 42814290.

### See Also

`SRV`

### Examples

    ## Data
    Sp=matrix(rnorm(10*13454,mean=0,sd=1), nrow=10,ncol=13454)

    ## Quotient probabilistic normalisation
    NormDat<-normalise(abs(Sp),'prob')

[Package mQTL version 1.0 Index]