R: HLA Loci and Serologic Response to Measles Vaccination

hla.demo {haplo.stats} | R Documentation

## HLA Loci and Serologic Response to Measles Vaccination

### Description

A data frame with genotypes at eleven HLA-region loci genotyped for 220 subjects, phase not known. Contains measles vaccination response with covariate data.

### Usage

    data(hla.demo)

### Format

A data frame with 220 observations on the following 26 variables.

`resp`

  numeric, Quantitative response to Measles Vaccination

`resp.cat`

  Category of vaccination response, a factor with levels `high` `low` `normal`

`male`

  numeric, indicator of gener, 1=male, 0=female

`age`

  numeric, subject's age

`DPB.a1`

  first allele of genotype

`DPB.a2`

  second allele of genotype

`DPA.a1`

  first allele of genotype

`DPA.a2`

  second allele of genotype

`DMA.a1`

  first allele of genotype

`DMA.a2`

  second allele of genotype

`DMB.a1`

  first allele of genotype

`DMB.a2`

  second allele of genotype

`TAP1.a1`

  first allele of genotype

`TAP1.a2`

  second allele of genotype

`TAP2.a1`

  first allele of genotype

`TAP2.a2`

  second allele of genotype

`DQB.a1`

  first allele of genotype

`DQB.a2`

  second allele of genotype

`DQA.a1`

  first allele of genotype

`DQA.a2`

  second allele of genotype

`DRB.a1`

  first allele of genotype

`DRB.a2`

  second allele of genotype

`B.a1`

  first allele of genotype

`B.a2`

  second allele of genotype

`A.a1`

  first allele of genotype

`A.a2`

  second allele of genotype

### Source

Data set kindly provided by Gregory A. Poland, M.D. and the Mayo Clinic Vaccine Research Group for illustration only, and my not be used for publication.

### References

Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA. "Score tests for association of traits with haplotypes when linkage phase is ambiguous." Amer J Hum Genet. 70 (2002): 425-434.

### Examples

    data(hla.demo)

[Package haplo.stats version 1.7.9 Index]