R: Protein Expression in Human Immune System Cells

Sachs {gss} | R Documentation

## Protein Expression in Human Immune System Cells

### Description

Data concerning protein expression levels in human immune system cells under stimulations.

### Usage

    data(Sachs)

### Format

A data frame containing 7466 cells, with flow cytometry measurements of 11 phosphorylated proteins and phospholipids, on the `log10` scale of the original.

`praf` | Raf phosphorylated at S259.
`pmek` | Mek1/mek2 phosphorylated at S217/S221.
`plcg` | Phosphorylation of phospholipase C-γ on Y783.
`pip2` | Phophatidylinositol 4,5-biphosphate.
`pip3` | Phophatidylinositol 3,4,5-triphosphate.
`p44.42` | Erk1/erk2 phosphorylated at T202/Y204.
`pakts473` | AKT phosphorylated at S473.
`pka` | Phosphorylation of of protein kinase A substrates on 3 sites.
`pkc` | Phosphorylation of of protein kinase C substrates on S660.
`p38` | Erk1/erk2 phosphorylated at T180/Y182.
`pjnk` | Erk1/erk2 phosphorylated at T183/Y185.

### Source

Sachs, K., Perez, O., Pe'er, D., Lauffenburger, D. A., and Nolan, G. P. (2005), Causal protein-signaling networks derived from multiparameter single-cell data. Science, 308 (5732), 523–529.

[Package gss version 2.2-2 Index]