R: Clinical Trial of Beta-Blockers

betablocker {flexmix} | R Documentation

## Clinical Trial of Beta-Blockers

### Description

22-centre clinical trial of beta-blockers for reducing mortality after myocardial infarction.

### Usage

    data("betablocker")

### Format

A data frame with 44 observations on the following 4 variables.

Deaths

  Number of deaths.

Total

  Total number of patients.

Center

  Number of clinical centre.

Treatment

  A factor with levels `Control` and `Treated`.

### Source

G. McLachlan and D. Peel. Finite Mixture Models, 2000. John Wiley and Sons Inc. http://www.maths.uq.edu.au/~gjm/DATA/mmdata.html

### References

M. Aitkin. Meta-analysis by random effect modelling in generalized linear models. Statistics in Medicine, 18, 2343–2351, 1999.

S. Yusuf, R. Peto, J. Lewis, R. Collins and P. Sleight. Beta blockade during and after myocardial infarction: an overview of the randomized trials. Progress in Cardiovascular Diseases, 27, 335–371, 1985.

### Examples

    data("betablocker", package = "flexmix")
    betaMix <- initFlexmix(cbind(Deaths, Total - Deaths) ~ 1 | Center,
                           data = betablocker, k = 3, nrep = 5,
                           model = FLXMRglmfix(family = "binomial",
                             fixed = ~Treatment))

[Package flexmix version 2.3-14 Index]