R: Ovarian Carcinoma

ocarcinoma {exactRankTests} | R Documentation

## Ovarian Carcinoma

### Description

Survival times of 35 women suffering ovarian carcinoma at stadium II and IIA.

### Usage

    data(ocarcinoma)

### Format

A data frame with 35 observations on the following 3 variables.

time

  time in days.

cens

  censoring indicator: 0 censored, 1 event.

stadium

  a factor with levels `II` and `IIA`.

### Details

Data from Fleming et al. (1980, 1984), reanalysed in Schumacher and Schulgen (2002).

### Source

Thomas R. Fleming, Judith R. O'Fallon, Peter C. O'Brien & David P. Harrington (1980), Modified Kolmogorov-Smirnov test procedures with applications to arbitrarily censored data. Biometrics, 36, 607–625.

Thomas R. Fleming, Stephanie J. Green & David P. Harrington (1984), Considerations of monitoring and evaluating treatment effects in clinical trials. Controlled Clinical Trials, 5, 55–66.

### References

Martin Schumacher & Gabi Schulgen (2002), Methodik klinischer Studien: methodische Grundlagen der Planung, Durchf\"uhrung und Auswertung. Springer, Heidelberg.

### Examples

    data(ocarcinoma)
    attach(ocarcinoma)
    # compute integer valued logrank scores
    logrsc <- cscores.Surv(cbind(time, cens), int=TRUE)
    # the test statistic
    lgT <- sum(logrsc[stadium == "II"])
    # p-value
    round(pperm(lgT, logrsc, m=sum(stadium=="II"), al="tw"), 4)

    # compute logrank scores and simulate p-value
    logrsc <- cscores.Surv(cbind(time, cens), int=FALSE)
    # the test statistic
    lgT <- sum(logrsc[stadium == "II"])
    # p-value
    round(pperm(lgT, logrsc, m=sum(stadium=="II"), al="tw", simulate=TRUE), 4)

[Package exactRankTests version 0.8-29 Index]