R: Clinical status, relapse, metastasis and death in 2982 women...

BrCa {Epi} | R Documentation

## Clinical status, relapse, metastasis and death in 2982 women with breast cancer.

### Description

This dataset is a transformation of the example dataset used by Crowther and Lambert in their multistate paper.

### Usage

    data(BrCa)

### Format

A data frame with 2982 observations on the following 17 variables:

`pid`

  Person-id; numeric

`year`

  Calendar year of diagnosis

`age`

  Age at diagnosis

`meno`

  Menopausal status; a factor with levels `pre` `post`

`size`

  Tumour size; a factor with levels `<=20 mm` `>20-50 mm` `>50 mm`

`grade`

  Tumour grade; a factor with levels `2` `3`

`nodes`

  Number of positive lymph nodes, a numeric vector

`pr`

  Progesteron receptor level

`pr.tr`

  Transformed progesteron level

`er`

  Estrogen receptor level

`hormon`

  Hormon therapy at diagnosis; a factor with levels `no` `yes`

`chemo`

  Chemotherapy treatment; a factor with levels `no` `yes`

`tor`

  Time of relapse, years since diagnosis

`tom`

  Time of metastasis, years since diagnosis

`tod`

  Time of death, years since diagnosis

`tox`

  Time of exit from study, years since diagnosis

`xst`

  Vital status at exit; a factor with levels `Alive` `Dead`

### Details

The dataset has been modified to contain the times (since diagnosis) of the events of interest, to comply with the usual structure of data.

### Source

The original data were extracted from: http://fmwww.bc.edu/repec/bocode/m/multistate_example.dta, this is modified representation of the same amount of information.

### References

The data were used as example in the paper by Crowther and Lambert: Parametric multistate survival models: Flexible modelling allowing transition-specific distributions with application to estimating clinically useful measures of effect differences; Stat Med 36 (29), pp 4719-4742, 2017. (No, it is not the paper, just the title.)

A parallel analysis using the `Lexis` machinery is available as: http://bendixcarstensen.com/AdvCoh/papers/bcMS.pdf

### Examples

    data(BrCa)

[Package Epi version 2.44 Index]