R: Analysis of Dose-Response Curves

# Analysis of Dose-Response Curves

## Documentation for package ‘drc’ version 3.0-1

- DESCRIPTION file.
- Package NEWS.

## Help Pages

A B C D E F G H I L M N O P R S T U V W Y

## -- A --

acidiq | Acifluorfen and diquat tested on Lemna minor.
actimL | Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
algae | Volume of algae as function of increasing concentrations of a herbicide
anova.drc | ANOVA for dose-response model fits
AR.2 | Asymptotic regression model
AR.3 | Asymptotic regression model
auxins | Effect of technical grade and commercially formulated auxin herbicides

## -- B --

backfit | Calculation of backfit values from a fitted dose-response model
baro5 | The modified baro5 function
BC.4 | The Brain-Cousens hormesis models
BC.5 | The Brain-Cousens hormesis models
bcl3 | The Brain-Cousens hormesis models
bcl4 | The Brain-Cousens hormesis models
boxcox.drc | Transform-both-sides Box-Cox transformation
braincousens | The Brain-Cousens hormesis models
bread.drc | Bread and meat for the sandwich

## -- C --

cedergreen | The Cedergreen-Ritz-Streibig model
chickweed | Germination of common chickweed (_Stellaria media_)
chickweed0 | Germination of common chickweed (_Stellaria media_)
CIcomp | Calculation of combination index for binary mixtures
CIcompX | Calculation of combination index for binary mixtures
coef.drc | Extract Model Coefficients
comped | Comparison of effective dose values
compParm | Comparison of parameters
confint.drc | Confidence Intervals for model parameters
cooks.distance.drc | Model diagnostics for nonlinear dose-response models
CRS.4a | The Cedergreen-Ritz-Streibig model
CRS.4b | The Cedergreen-Ritz-Streibig model
CRS.4c | The Cedergreen-Ritz-Streibig model
CRS.5a | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
CRS.5b | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
CRS.5c | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
CRS.6 | The Cedergreen-Ritz-Streibig model

## -- D --

daphnids | Daphnia test
decontaminants | Performance of decontaminants used in the culturing of a micro-organism
deguelin | Deguelin applied to chrysanthemum aphis
drm | Fitting dose-response models
drmc | Sets control arguments

## -- E --

earthworms | Earthworm toxicity test
ED | Estimating effective doses
ED.drc | Estimating effective doses
EDcomp | Comparison of relative potencies between dose-response curves
estfun.drc | Bread and meat for the sandwich
etmotc | Effect of erythromycin on mixed sewage microorganisms
EXD.2 | Exponential decay model
EXD.3 | Exponential decay model

## -- F --

finney71 | Example from Finney (1971)
fitted.drc | Extract fitted values from model
FPL.4 | Fractional polynomial-logistic dose-response models
fplogistic | Fractional polynomial-logistic dose-response models

## -- G --

G.2 | Mean function for the Gompertz dose-response or growth curve
G.3 | Mean function for the Gompertz dose-response or growth curve
G.3u | Mean function for the Gompertz dose-response or growth curve
G.4 | Mean function for the Gompertz dose-response or growth curve
G.aparine | Herbicide applied to Galium aparine
gammadr | Gamma dose-response model
gaussian | Normal and log-normal biphasic dose-response models
genBliss | Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
genBliss2 | Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
genLoewe | Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
genLoewe2 | Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
genursa | Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
germination | Germination of three crops
getInitial | Showing starting values used
getMeanFunctions | Display available dose-response models
glymet | Glyphosate and metsulfuron-methyl tested on algae.
gompertz | Mean function for the Gompertz dose-response or growth curve
gompertzd | The derivative of the Gompertz function

## -- H --

H.virescens | Mortality of tobacco budworms
hatvalues.drc | Model diagnostics for nonlinear dose-response models
heartrate | Heart rate baroreflexes for rabbits

## -- I --

iceLoewe.1 | Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
iceLoewe2.1 | Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
isobole | Creating isobolograms

## -- L --

L.3 | The logistic model
L.4 | The logistic model
L.5 | The logistic model
l2 | The two-parameter log-logistic function
l3 | The three-parameter log-logistic function
l3u | The three-parameter log-logistic function
l4 | The four-parameter log-logistic function
l5 | The five-parameter log-logistic function
leaflength | Leaf length of barley
lepidium | Dose-response profile of degradation of agrochemical using lepidium
lettuce | Hormesis in lettuce plants
lgaussian | Normal and log-normal biphasic dose-response models
lin.test | Lack-of-fit test for the mean structure based on cumulated residuals
LL.2 | The two-parameter log-logistic function
LL.3 | The three-parameter log-logistic function
LL.3u | The three-parameter log-logistic function
LL.4 | The four-parameter log-logistic function
LL.5 | The five-parameter log-logistic function
LL2.2 | The two-parameter log-logistic function
LL2.3 | The three-parameter log-logistic function
LL2.3u | The three-parameter log-logistic function
LL2.4 | The four-parameter log-logistic function
LL2.5 | The five-parameter log-logistic function
llogistic | The log-logistic function
llogistic2 | The log-logistic function
LN.2 | Log-normal dose-response model
LN.3 | Log-normal dose-response model
LN.3u | Log-normal dose-response model
LN.4 | Log-normal dose-response model
lnormal | Log-normal dose-response model
logistic | The logistic model
logLik.drc | Extracting the log likelihood

## -- M --

M.bahia | Effect of an effluent on the growth of mysid shrimp
maED | Estimation of ED values using model-averaging
MAX | Maximum mean response
mecter | Mechlorprop and terbythylazine tested on Lemna minor
metals | Data from heavy metal mixture experiments
methionine | Weight gain for different methionine sources
mixture | Fitting binary mixture models
ml3a | The Cedergreen-Ritz-Streibig model
ml3b | The Cedergreen-Ritz-Streibig model
ml3c | The Cedergreen-Ritz-Streibig model
ml4a | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
ml4b | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
ml4c | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
MM.2 | Michaelis-Menten model
MM.3 | Michaelis-Menten model
modelFit | Assessing the model fit
mr.test | Mizon-Richard test for dose-response models
mselect | Dose-response model selection
multi2 | Multistage dose-response model with quadratic terms

## -- N --

nasturtium | Dose-response profile of degradation of agrochemical using nasturtium
NEC | Dose-response model for estimation of no effect concentration (NEC).
NEC.2 | Dose-response model for estimation of no effect concentration (NEC).
NEC.3 | Dose-response model for estimation of no effect concentration (NEC).
NEC.4 | Dose-response model for estimation of no effect concentration (NEC).
neill.test | Neill's lack-of-fit test for dose-response models
noEffect | Testing if there is a dose effect at all

## -- O --

O.mykiss | Test data from a 21 day fish test

## -- P --

P.promelas | Effect of sodium pentachlorophenate on growth of fathead minnow
plot.drc | Plotting fitted dose-response curves
plotFACI | Calculation of combination index for binary mixtures
PR | Expected or predicted response
predict.drc | Prediction
predict.mrdrc | Prediction
print.drc | Printing key features
print.summary.drc | Printing summary of non-linear model fits

## -- R --

rdrm | Simulating a dose-response curve
relpot | Comparison of relative potencies between dose-response curves
residuals.drc | Extracting residuals from the fitted dose-response model
RScompetition | Competition between two biotypes
ryegrass | Effect of ferulic acid on growth of ryegrass

## -- S --

S.alba | Potency of two herbicides
S.capricornutum | Effect of cadmium on growth of green alga
searchdrc | Searching through a range of initial parameter values to obtain convergence
secalonic | Root length measurements
selenium | Data from toxicology experiments with selenium
simDR | Simulating ED values under various scenarios
spinach | Inhibition of photosynthesis
summary.drc | Summarising non-linear model fits

## -- T --

terbuthylazin | The effect of terbuthylazin on growth rate
twophase | Two-phase dose-response model

## -- U --

ucedergreen | The Cedergreen-Ritz-Streibig model
UCRS.4a | The Cedergreen-Ritz-Streibig model
UCRS.4b | The Cedergreen-Ritz-Streibig model
UCRS.4c | The Cedergreen-Ritz-Streibig model
UCRS.5a | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
UCRS.5b | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
UCRS.5c | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
uml3a | The Cedergreen-Ritz-Streibig model
uml3b | The Cedergreen-Ritz-Streibig model
uml3c | The Cedergreen-Ritz-Streibig model
uml4a | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
uml4b | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
uml4c | Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
update.drc | Updating and re-fitting a model
ursa | Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction

## -- V --

vcov.drc | Calculating variance-covariance matrix for objects of class 'drc'
vinclozolin | Vinclozolin from AR in vitro assay

## -- W --

W1.2 | The two-parameter Weibull functions
W1.3 | The three-parameter Weibull functions
W1.3u | The three-parameter Weibull functions
W1.4 | The four-parameter Weibull functions
w2 | The two-parameter Weibull functions
W2.2 | The two-parameter Weibull functions
W2.3 | The three-parameter Weibull functions
W2.3u | The three-parameter Weibull functions
W2.4 | The four-parameter Weibull functions
W2x.3 | The three-parameter Weibull functions
W2x.4 | The four-parameter Weibull functions
w3 | The three-parameter Weibull functions
w4 | The four-parameter Weibull functions
weibull1 | Weibull model functions
weibull2 | Weibull model functions
weibull2x | Weibull model functions

## -- Y --

yieldLoss | Calculating yield loss parameters