R: Gene expression signatures for p53 mutation status in 250...

breastcancer {doBy} | R Documentation

## Gene expression signatures for p53 mutation status in 250 breast cancer samples

### Description

Perturbations of the p53 pathway are associated with more aggressive and therapeutically refractory tumours. We preprocessed the data using Robust Multichip Analysis (RMA). Dataset has been truncated to the 1000 most informative genes (as selected by Wilcoxon test statistics) to simplify computation. The genes have been standardised to have zero mean and unit variance (i.e. z-scored).

### Usage

    data(breastcancer)

### Format

A data frame with 250 observations on the following 1001 variables.

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`B.234954_at`

  a numeric vector

`B.234992_x_at`

  a numeric vector

`B.235040_at`

  a numeric vector

`B.235046_at`

  a numeric vector

`B.235117_at`

  a numeric vector

`B.235124_at`

  a numeric vector

`B.235181_at`

  a numeric vector

`B.235193_at`

  a numeric vector

`B.235363_at`

  a numeric vector

`B.235369_at`

  a numeric vector

`B.235425_at`

  a numeric vector

`B.235542_at`

  a numeric vector

`B.235545_at`

  a numeric vector

`B.235547_at`

  a numeric vector

`B.235570_at`

  a numeric vector

`B.235572_at`

  a numeric vector

`B.235609_at`

  a numeric vector

`B.235662_at`

  a numeric vector

`B.235709_at`

  a numeric vector

`B.235771_at`

  a numeric vector

`B.235786_at`

  a numeric vector

`B.235789_at`

  a numeric vector

`B.235800_at`

  a numeric vector

`B.236050_at`

  a numeric vector

`B.236064_at`

  a numeric vector

`B.236312_at`

  a numeric vector

`B.236641_at`

  a numeric vector

`B.236787_at`

  a numeric vector

`B.236953_s_at`

  a numeric vector

`B.237086_at`

  a numeric vector

`B.237168_at`

  a numeric vector

`B.237301_at`

  a numeric vector

`B.237339_at`

  a numeric vector

`B.238001_at`

  a numeric vector

`B.238045_at`

  a numeric vector

`B.238075_at`

  a numeric vector

`B.238077_at`

  a numeric vector

`B.238116_at`

  a numeric vector

`B.238425_at`

  a numeric vector

`B.238447_at`

  a numeric vector

`B.238656_at`

  a numeric vector

`B.238756_at`

  a numeric vector

`B.238781_at`

  a numeric vector

`B.238898_at`

  a numeric vector

`B.239002_at`

  a numeric vector

`B.239349_at`

  a numeric vector

`B.239432_at`

  a numeric vector

`B.239758_at`

  a numeric vector

`B.239890_s_at`

  a numeric vector

`B.240099_at`

  a numeric vector

`B.240422_at`

  a numeric vector

`B.241310_at`

  a numeric vector

`B.241408_at`

  a numeric vector

`B.241577_at`

  a numeric vector

`B.241789_at`

  a numeric vector

`B.241937_s_at`

  a numeric vector

`B.242218_at`

  a numeric vector

`B.242255_at`

  a numeric vector

`B.242323_at`

  a numeric vector

`B.242560_at`

  a numeric vector

`B.242657_at`

  a numeric vector

`B.242890_at`

  a numeric vector

`B.243754_at`

  a numeric vector

`B.243806_at`

  a numeric vector

`B.244116_at`

  a numeric vector

`B.244375_at`

  a numeric vector

`B.244571_s_at`

  a numeric vector

`B.244677_at`

  a numeric vector

`B.244696_at`

  a numeric vector

`B.AFFX.HUMGAPDH.M33197_3_at`

  a numeric vector

`B.AFFX.HUMGAPDH.M33197_M_at`

  a numeric vector

`code`

  a factor with levels `case` `control`

### Details

The factor `code` defines whether there was a mutation in the p53 sequence (code=case) or not (code=control).

### Source

Dr. Chris Holmes, c.holmes at stats dot. ox . ac .uk

### References

Miller et al (2005, PubMed ID:16141321)

### Examples

    data(breastcancer)
    ## maybe str(breastcancer) ; plot(breastcancer) ...

[Package doBy version 4.5-15 Index]