R: Ovarian Carcinoma

ocarcinoma {coin} | R Documentation

## Ovarian Carcinoma

### Description

Survival times of 35 women suffering from ovarian carcinoma at stadium II and IIA.

### Usage

    ocarcinoma

### Format

A data frame with 35 observations on 3 variables.

`time`

  time (days).

`stadium`

  a factor with levels `"II"` and `"IIA"`.

`event`

  status indicator for `time`: `FALSE` for censored observations and `TRUE` otherwise.

### Details

Data from Fleming et al. (1980) and Fleming, Green and Harrington (1984). Reanalysed in Schumacher and Schulgen (2002).

### Source

Fleming, T. R., Green, S. J. and Harrington, D. P. (1984). Considerations of monitoring and evaluating treatment effects in clinical trials. Controlled Clinical Trials 5(1), 55–66.

Fleming, T. R., O'Fallon, J. R., O'Brien, P. C. and Harrington, D. P. (1980). Modified Kolmogorov-Smirnov test procedures with applications to arbitrarily censored data. Biometrics 36(4), 607–625.

### References

Schumacher, M. and Schulgen, G. (2002). Methodik Klinischer Studien: Methodische Grundlagen der Planung, Durchführung und Auswertung. Heidelberg: Springer.

### Examples

    ## Exact logrank test
    lt <- logrank_test(Surv(time, event) ~ stadium, data = ocarcinoma,
                       distribution = "exact")

    ## Test statistic
    statistic(lt)

    ## P-value
    pvalue(lt)

[Package coin version 1.1-3 Index]