R: Lymph-node-negative primary breast tumors

breast {beeswarm} | R Documentation

## Lymph-node-negative primary breast tumors

### Description

Tumor molecular measurements and outcome from breast cancer patients.

### Usage

    data(breast)

### Format

A data frame with 286 observations on the following 5 variables.

`ER`

  Estrogen receptor status (factor with levels `neg`, `pos`)

`ESR1`

  Expression of the ESR1 gene (numeric)

`ERBB2`

  Expression of the ERBB2 gene (numeric)

`time_survival`

  Time in months (numeric)

`event_survival`

  Coded event: 0 = censored, 1 = metastasis (numeric)

### Details

ER, ESR1, and ERBB2 were measured on a tumor specimen taken at surgery (time = 0).

ESR1 and ERBB2 expression values were determined by microarray probe sets 205225_at and 216836_s_at using RMA-normalized data.

### Source

Wang Y, Klijn JG, Zhang Y, Sieuwerts AM, Look MP, Yang F, Talantov D, Timmermans M, Meijer-van Gelder ME, Yu J, Jatkoe T, Berns EM, Atkins D, Foekens JA. Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet. 2005 Feb 19-25;365(9460):671-9.

### Examples

      data(breast)

      with(breast,
        plot(ESR1, ERBB2, col = as.numeric(ER))
      )

[Package beeswarm version 0.4.0 Index]