| .ExtendedScores | Make a smooth surface for scores |
| AddNoise | Add noise to response value |
| Bliss | Calculate Bliss synergy score |
| CalculateSynergy | Calculate the synergy scores for drug combinations |
| CorrectBaseLine | Base line correction |
| ExtractSingleDrug | Extract single drug response from matrix |
| FindModelType | Find the type of model used for fitting dose response data |
| FitDoseResponse | Fitting single drug dose-response model |
| HSA | Calculate HSA synergy score |
| ImputeNA | Impute missing value with nearest values |
| kriging | Kriging |
| Loewe | Calculate Loewe synergy score |
| mathews_screening_data | A high-throughput drug combination screening data |
| PlotDoseResponse | Visualize the drug combination dose-response data |
| PlotSynergy | Drug interaction landscape |
| ReshapeData | Pre-processe the response data for furhter calculation and plot |
| ZIP | Calculate Delta synergy score based on ZIP model |