#Gene_ID	Gene_name	Codon_pos	Ref_nuc	Ref_codon	Res_codon	Resistance	PMID	Mechanism	Notes	Required_mut
gyrA	gyrA	70	GCC	A	T	Nalidixic acid, Ciprofloxacin	8384814	Target modification		
gyrA	gyrA	85	GAT	D	Y	Nalidixic acid, Ciprofloxacin	18031331	Target modification	Phenotype described only in association with other mutations (T86), unknown phenotype if the present mutation occurs alone	gyrA_T86I.A.K.V
gyrA	gyrA	86	ACA	T	I,A,K,V	Nalidixic acid, Ciprofloxacin	11266291,Unpublished,8384814,16713726	Target modification		
gyrA	gyrA	90	GAT	D	A,N,T	Nalidixic acid, Ciprofloxacin	8384814,8384814,16713726	Target modification		
gyrA	gyrA	104	CCA	P	S	Nalidixic acid, Ciprofloxacin	16713726	Target modification	Phenotype described only in association with other mutations (R285), unknown phenotype if the present mutation occurs alone	gyrA_R285K
gyrA_2	gyrA_2	70	GCC	A	T	Nalidixic acid, Ciprofloxacin	8384814	Target modification		
gyrA_2	gyrA_2	85	GAT	D	Y	Nalidixic acid, Ciprofloxacin	18031331	Target modification	Phenotype described only in association with other mutations (T86), unknown phenotype if the present mutation occurs alone      gyrA_T86I.A.K.V	
gyrA_2	gyrA_2	86	ACA	T	I,A,K,V	Nalidixic acid, Ciprofloxacin	11266291,Unpublished,8384814,16713726	Target modification		
gyrA_2	gyrA_2	90	GAT	D	A,N,T	Nalidixic acid, Ciprofloxacin	8384814,8384814,16713726	Target modification		
gyrA_2	gyrA_2	104	CCA	P	S	Nalidixic acid, Ciprofloxacin	16713726	Target modification	Phenotype described only in association with other mutations (R285), unknown phenotype if the present mutation occurs alone     gyrA_R285K	
23S	23S	2074	A	A	G,T,C	Azithromycin, Erythromycin, Clindamycin, Telithromycin	16713726,16713726,16713726	Target modification		
23S	23S	2075	A	A	G	Azithromycin, Erythromycin, Clindamycin, Telithromycin	16713726	Target modification		
rpsL	rpsL	43	AAA	K	R	Streptomycin	20370506	Target modification		
rpsL	rpsL	88	AAA	K	R,E,Q	Streptomycin	20370506	Target modification		
porA	porA	56	GGT	G	D	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
porA	porA	56	GGC	G	D	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
porA	porA	56	GGA	G	D	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
porA	porA	56	GGC	G	D	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
cmeA	cmeA	366	GCT	A	T	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
cmeA	cmeA	366	GCC	A	T	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
cmeA	cmeA	366	GCA	A	T	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
cmeA	cmeA	366	GCG	A	T	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
cmeB	cmeB	45	AAA	K	E	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
cmeB	cmeB	45	AAG	K	E	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
cmeR	cmeR	172	CCT	P	S	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
cmeR	cmeR	172	CCC	P	S	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
cmeR	cmeR	172	CCA	P	S	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
cmeR	cmeR	172	CCG	P	S	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
# Indels										
porA    porA    139	-	ins	ND	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance. The actual insertion is Asn139_Ala140insAsp, but is picked up by BLAST as N139_N139delinsND.
porA	porA	139	-	ins	D	Ertapenem, Meropenem 	37358443	Efflux	Contributes to increased resistance 	
