cell identity from single cell RNA-Seq data


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Documentation for package ‘singleCellNet’ version 0.1.0

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avgGeneCat Average Category Gene Expressions
cn_barplot_grnSing_base barplot this specific GRN
cn_classAssess Assess classifiers based on validation data
cn_clPerf determine performance of classification at given threshold
cn_computeAUCPR compute AUPCR
cn_correctZmat make Inf and -Inf values sensible
cn_eval run cn_clPerf across thresholds
cn_findSensAt return the sens at given FPR
cn_rectArea compute area of rect given by
compareGenePairs Compile genePairs comparison matrix
csRenameOrth enable cross-species comparison
downSampleW weighted subtraction from mapped reades
extractSCE extract sampTab and expDat sce object into regular S3 objects
extractSeurat extract sampTab and expDat seurat object into regular S3 objects
findAvgLabel Make training label
findBestPairs finds the best pairs to use
findClassyGenes Find Classifier-Worthy Gene Candidates
GEP_makeMean row average (or median) based on groups
getClassGenes Find Classy Genes
getSpecGenes get the genes specific to each diffexp in a list of them
gnrAll find genes higher in a cluster compared to all other cells
gnrBP find best pairs
harmonize harmonize data sets
hm_enr heatmap of the enrichment result
hm_gpa_sel heatmap genes and groups
load10x Loads 10x data mtx
makeGeneCompareTab Make Gene Comparison Table
mclust_Mat run Mclust on an expression matrix
mergeLoad10x Loads 10x data mtx
pair_transform makes complete gene-to-gene comparison
pca_to_tsne make tsne from pca
plotDBscan plot tsne results
plotGeneComparison Gene expression plotting
plotGPApca plot gpa res
plot_class_PRs Plot results of sc_classAssess
probTrans transform mclust class res to expression prob estimates
ptGetTop Find the best gene pairs for training
query_transform makes complete gene-to-gene comparison
randomize randomize data matrix
reorderCellsByGrp re-order cells for plotting
rf_classPredict classify samples
scn_extract_SN_DF returns a DF of: sample_id, description, ctt, subnet_name, score
scn_make_tVals Estimate gene expression dist in CTs
scn_netScores GRN status
scn_normalizeScores Normalize grn status as compared to training data
scn_predict Predict query using broad class classifier
scn_rawScore computes the raw score for a gene as xmax-abs(zscore).
scn_score GRN status
scn_train Training
scn_trainGRN Figure out normalization factors for GRNs, and norm training data
sc_Accu Assess classifiers based on validation data
sc_classAssess assess the classifiers performance based on validation data
sc_classThreshold determine performance of classification at given class threshold
sc_filterCells find cells that pass criteria
sc_filterGenes find genes that pass criteria
sc_findEnr finds genes higher in one group vs others
sc_hmClass heatmap of the classification result
sc_makeClassifier Make Classifier
sc_trans_rnaseq weighted subtraction from mapped reades and log applied to all
skylineClass Skyline waterfall
tsneMultsimp plot tsne and genes
utils_loadObject loads an R object when you don't know the name
utils_myDate print date
utils_myDist 1-PCC distance
utils_stripwhite strip whitespace from a string
utils_strip_fname reduces full path to filename
weighted_down weighted subtraction from mapped reades, applied to all