Extracts SNV, indel, and SV signatures from vcf files.


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Documentation for package ‘mutSigExtractor’ version 1.14

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DBS_SIGNATURE_PROFILES DBS signature profiles
DBS_TYPES Look up table for doublet base substitution types and reverse complement sequences
extractSigsDbs Extract doublet substitution signatures
extractSigsIndel Extract indel signatures
extractSigsSnv Extract single nucleotide variant signatures
extractSigsSv Extract structural variant signatures
fitToSignatures Linear least-squares (non-negative) fitting
getContextsDbs Extract doublet base substitution contexts
getContextsIndel Extract indel sequence, type and length
getContextsSnv Extract trinucleotide contexts
getContextsSv Determine SV type and length
getInfoValues Get values from INFO field
hello Hello, World!
indelSeqFlanksStartEnd Get the start/end positions for the left/right flanks of an indel
nBasesMH Calculate the number of bases that are homologous to the 3' flanking sequence
nCopiesAlongFlank Calculate the number of copies of the indel sequence are present in the flank sequence
readSigsAsDf Read multiple files outputed my mutSigExtractor into a data frame
readVcfFields Read vcf into R as data frame
SBS_SIGNATURE_PROFILES_V2 SBS signature profiles (original 30)
splitDfRegex Split data frame or matrix using regex on colnames
SV_SIGNATURE_PROFILES SV signature profiles
transformContexts Various transformation of contexts (e.g. into mutational signatures)
variantsFromVcf Extract relevant variant info for extracting SNV, indel, and SV signatures.