{% extends "humanization/humanness_layout.html" %} {% set title = "Humanness Report" %} {% set SORTABLE = 'sortable' if not has_next_page and not has_prev_page %} {% block main %}
Antibody | Heavy chain | Light chain | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Name | OASis Identity {{ info_icon('Fraction of 9-mer peptides considered human based on given prevalence threshold') }} |
OASis Percentile {{ info_icon('Percentile of OASis identity among therapeutic mAbs at the current prevalence threshold. Zero percentile corresponds to the least human and 100% percentile corresponds to the most human mAb in the clinic, including all clinical stage human, humanized and murine therapeutics.') }} |
Germline Content {{ info_icon('Sequence identity with nearest heavy and light human germline sequences') }} |
OASis Identity {{ info_icon('Fraction of heavy chain 9-mer peptides considered human based on given prevalence threshold') }} |
OASis Percentile {{ info_icon('Percentile of heavy chain OASis identity among therapeutic mAbs at the current prevalence threshold. Zero percentile corresponds to the least human and 100% percentile corresponds to the most human mAb in the clinic, including all clinical stage human, humanized and murine therapeutics.') }} |
Germline Gene {{ info_icon('Nearest human heavy germline gene based on sequence similarity.') }} |
Germline Content {{ info_icon('Sequence identity with nearest human heavy germline sequence') }} |
OASis Identity {{ info_icon('Fraction of light chain 9-mer peptides considered human based on given prevalence threshold') }} |
OASis Percentile {{ info_icon('Percentile of light chain OASis identity among therapeutic mAbs at the current prevalence threshold. Zero percentile corresponds to the least human and 100% percentile corresponds to the most human mAb in the clinic, including all clinical stage human, humanized and murine therapeutics.') }} |
Germline Gene {{ info_icon('Nearest human light germline gene based on sequence similarity.') }} |
Germline Content {{ info_icon('Sequence identity with nearest human light germline sequence') }} |
Actions | ||
{{ result.input.name }} | {% if isinstance(result, Exception) %}Failed: {{ result }} | {% else %} {% set min_subj = result.oasis_params.min_fraction_subjects %}{{ '{:.0%}'.format(result.humanness.get_oasis_identity(min_subj)) }} | {{ '{:.0%}'.format(result.humanness.get_oasis_percentile(min_subj)) }} | {{ '{:.0%}'.format(result.humanness.get_germline_content()) }} | {{ chain_row(result.humanness.vh, min_subj) }} {{ chain_row(result.humanness.vl, min_subj) }} {% endif %}Detail |