{% extends "humanization/humanness_layout.html" %} {% set title = "Humanness Report" %} {% set SORTABLE = 'sortable' if not has_next_page and not has_prev_page %} {% block main %}
{{ icon('chevron-left') }} Input

Humanness report results

{% for result in results %} {% if isinstance(result, Exception) %} {% else %} {% set min_subj = result.oasis_params.min_fraction_subjects %} {{ chain_row(result.humanness.vh, min_subj) }} {{ chain_row(result.humanness.vl, min_subj) }} {% endif %} {% endfor %}
Antibody Heavy chain Light chain
Name OASis
Identity {{ info_icon('Fraction of 9-mer peptides considered human based on given prevalence threshold') }}
OASis
Percentile {{ info_icon('Percentile of OASis identity among therapeutic mAbs at the current prevalence threshold. Zero percentile corresponds to the least human and 100% percentile corresponds to the most human mAb in the clinic, including all clinical stage human, humanized and murine therapeutics.') }}
Germline
Content {{ info_icon('Sequence identity with nearest heavy and light human germline sequences') }}
OASis
Identity {{ info_icon('Fraction of heavy chain 9-mer peptides considered human based on given prevalence threshold') }}
OASis
Percentile {{ info_icon('Percentile of heavy chain OASis identity among therapeutic mAbs at the current prevalence threshold. Zero percentile corresponds to the least human and 100% percentile corresponds to the most human mAb in the clinic, including all clinical stage human, humanized and murine therapeutics.') }}
Germline
Gene {{ info_icon('Nearest human heavy germline gene based on sequence similarity.') }}
Germline
Content {{ info_icon('Sequence identity with nearest human heavy germline sequence') }}
OASis
Identity {{ info_icon('Fraction of light chain 9-mer peptides considered human based on given prevalence threshold') }}
OASis
Percentile {{ info_icon('Percentile of light chain OASis identity among therapeutic mAbs at the current prevalence threshold. Zero percentile corresponds to the least human and 100% percentile corresponds to the most human mAb in the clinic, including all clinical stage human, humanized and murine therapeutics.') }}
Germline
Gene {{ info_icon('Nearest human light germline gene based on sequence similarity.') }}
Germline
Content {{ info_icon('Sequence identity with nearest human light germline sequence') }}
Actions
{{ result.input.name }}Failed: {{ result }}{{ '{:.0%}'.format(result.humanness.get_oasis_identity(min_subj)) }} {{ '{:.0%}'.format(result.humanness.get_oasis_percentile(min_subj)) }} {{ '{:.0%}'.format(result.humanness.get_germline_content()) }} Detail
{% if has_next_page or has_prev_page %}
{% if has_prev_page %} < Previous page {% else %} < Previous page {% endif %} {% if has_next_page %} Next page > {% else %} Next page > {% endif %}
{% endif %} {% endblock %} {% macro chain_row(chain_humanness, min_subj) %} {% if chain_humanness %} {{ '{:.0%}'.format(chain_humanness.get_oasis_identity(min_subj)) }} {{ '{:.0%}'.format(chain_humanness.get_oasis_percentile(min_subj)) }} {{ chain_humanness.v_germline_names[0] }} {{ '{:.0%}'.format(chain_humanness.get_germline_content()) }} {% else %} - - - - {% endif %} {% endmacro %}